Peptide · Longevity & anti-aging
Epitalon is a synthetic tetrapeptide derived from epithalamin. Studied for telomerase activation and circadian regulation.
Epitalon is a synthetic tetrapeptide derived from epithalamin. Studied for telomerase activation and circadian regulation.
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed in Russia by Vladimir Khavinson. It is hypothesized to act on the pineal gland to stimulate telomerase activity and lengthen telomeres, with proposed anti-aging effects. Russian research suggests effects on melatonin secretion, immune function, and longevity. Western clinical evidence is sparse.
Russian clinical research; limited Western trials.
Compounded — not FDA-approved.
Common protocols: 5–10 mg subcutaneous daily for 10–20 day cycles, repeated 1–4 times yearly. Dosing protocols vary widely; the Khavinson research used different cycle structures than what is commonly used in Western longevity-medicine settings.
Dosing in research and clinical-use contexts varies. Specific protocols should always be set by a prescribing clinician, not by patient-direct sources.
Generally well-tolerated in available data. Reported side effects are minimal; injection-site reactions are the most common. Long-term safety is not well-characterized in Western clinical settings.
Often layered into broader longevity protocols with NAD+, NMN, GHK-Cu, and lifestyle interventions. Standalone use is also common.
Most peptides discussed on this page are compounded products requiring a prescription from a licensed clinician. Reputable telehealth peptide programs include physician-led oversight, accredited compounding pharmacies, and clear regulatory framing. For weight-management GLP-1 programs, see our provider reviews.
Epitalon is a synthetic tetrapeptide derived from epithalamin. Studied for telomerase activation and circadian regulation.
Compounded — not FDA-approved.
Uses include: Sleep regulation (research), Longevity stack component. This is research and clinical-use context, not a recommendation. Always work with a licensed clinician.
Russian clinical research; limited Western trials.
Reported dosing: 5–10 mg cycles. Actual dosing should always be determined by your prescribing clinician, not by online sources.
Russian research suggests effects on telomerase activity. Western replication is limited. Treat the longevity claims as preliminary.
No. Available through compounding pharmacies in the US.