Medication
Zepbound is FDA-approved tirzepatide for chronic weight management. SURMOUNT-1 trial reported a mean ~22.5% body-weight reduction at 72 weeks at the highest dose, the largest effect size of any approved weight-loss medication. List price approximately $1,086/month.
| Generic name | tirzepatide |
| Brand manufacturer | Eli Lilly |
| FDA indication | Chronic weight management in adults with BMI ≥30 or ≥27 with comorbidity; obstructive sleep apnea in adults with obesity |
| FDA approval year | 2023 |
| Form | Subcutaneous injection (prefilled pen and single-dose vial) |
| Schedule | Once weekly |
| List price (cash) | $1086/month |
For drug-class comparisons, see our medication-comparison hub:
Compounded tirzepatide is available through telehealth at $249–$499/month. Compounded products are not FDA-approved as finished drugs and are prepared by licensed compounding pharmacies on a per-patient basis. April 2026 FDA guidance applies to compounded GLP-1 advertising and prescribing. See our compounded vs brand-name guide for details.
Reputable telehealth options for compounded tirzepatide:
Coverage varies significantly by carrier and employer plan. See our insurance hub for plan-specific guidance:
Zepbound is the brand name for tirzepatide, manufactured by Eli Lilly. Zepbound is FDA-approved tirzepatide for chronic weight management. SURMOUNT-1 trial reported a mean ~22.5% body-weight reduction at 72 weeks at the highest dose, the largest effect size of any approv
Zepbound list price is approximately $1086/month. Insurance may cover it with prior authorization for FDA-approved indications. Compounded tirzepatide is available at $249–$499/month.
FDA-approved 2023. Indication: Chronic weight management in adults with BMI ≥30 or ≥27 with comorbidity; obstructive sleep apnea in adults with obesity.
Doses available: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg. Schedule: Once weekly. Always follow your prescribing clinician's titration plan.
See our medication comparisons hub for head-to-head pages on Wegovy vs Zepbound, Ozempic vs Wegovy, and semaglutide vs tirzepatide.
Note: This page is an editorial overview, not medical advice. Always consult a licensed clinician about whether Zepbound is appropriate for you.