Peptide · Cognitive enhancement
Selank is a synthetic analog of tuftsin, studied as an anxiolytic and nootropic.
Selank is a synthetic analog of tuftsin, studied as an anxiolytic and nootropic.
Selank is a synthetic heptapeptide developed in Russia, derived from the human protein tuftsin. The proposed mechanism involves modulation of GABAergic signaling and BDNF (brain-derived neurotrophic factor) expression, producing anxiolytic and nootropic effects without sedation, dependence, or withdrawal seen with benzodiazepines.
Russian clinical research; limited Western trials.
Compounded — not FDA-approved.
Most common form: intranasal spray, 250–500 mcg per dose, 2–3 times daily. Subcutaneous injectable dosing also exists at similar microgram ranges. Cycle length is typically 2–4 weeks on, with breaks.
Dosing in research and clinical-use contexts varies. Specific protocols should always be set by a prescribing clinician, not by patient-direct sources.
Generally well-tolerated. Reported side effects: mild fatigue, occasional headache, nasal irritation with the intranasal route. Not associated with dependence or withdrawal in available data.
Selank is commonly combined with semax (a related Russian peptide with more cognitive-stimulant effects) for combined anxiolytic + cognitive support. Some protocols pair selank with NAD+ for energy and cognition.
Most peptides discussed on this page are compounded products requiring a prescription from a licensed clinician. Reputable telehealth peptide programs include physician-led oversight, accredited compounding pharmacies, and clear regulatory framing. For weight-management GLP-1 programs, see our provider reviews.
Selank is a synthetic analog of tuftsin, studied as an anxiolytic and nootropic.
Compounded — not FDA-approved.
Uses include: Anxiety relief (research), Cognitive support (research). This is research and clinical-use context, not a recommendation. Always work with a licensed clinician.
Russian clinical research; limited Western trials.
Reported dosing: Intranasal, 250–500 mcg per dose. Actual dosing should always be determined by your prescribing clinician, not by online sources.
Selank is approved in Russia. It is not FDA-approved in the US. Available through compounding pharmacies in the US under prescription.
Selank has anxiolytic effects without sedation, dependence, or withdrawal. Effect strength is generally milder than benzodiazepines but with a much better safety profile for daily use.